The Start Line Is the Hardest Part: Why Most Teams Don’t Know Where to Begin

Let’s just say it:
Starting is often the hardest part — especially in pharma.
Not because you’re lazy.
Not because your team doesn’t care.
But because the problem is just… big.
You’ve got post-inspection cleanup, launch timelines, shifting regulatory expectations, and a project plan that’s either 1,000 lines long or totally blank. Sometimes both.
We’ve been there. And we’ve seen what happens when companies try to “just start anywhere.” It’s usually a combo of:
  • Hiring 4 different consultants (none of whom talk to each other)
  • Drafting a plan with so many contingencies it never moves
  • Building a Gantt chart so detailed it becomes the work
  • Hoping an internal hero magically emerges to lead it
Here’s the truth: when everything is on fire, “starting somewhere” is not a strategy.
It’s delay in disguise.
What You Actually Need Is a Start Line
We don’t mean a 3-month diagnostic or a 74-page slide deck. We mean:
  • What needs to happen first
  • Who owns what
  • What resources you’ll need
  • What you can ignore (at least for now)
We call this the Start Line. And we build it before we start charging hours or promising timelines.
Because clarity isn’t a deliverable. It’s a prerequisite.
Why Most Consultants Skip This Step
Frankly, it’s easier to just parachute into your chaos, bill a few hundred hours, and leave behind a “strategic roadmap” you’ll never use.
But that’s not what we do.
We built Two Pharma Guys because we were tired of watching smart people flail inside well-funded companies — not because they didn’t care, but because no one had given them a clear starting point.
We’re here to change that.
What Our Start Line Looks Like
If you’re wondering what it looks like to define the start line with us, here’s a sample:
  • We show up, usually with coffee and some hard questions
  • We listen (closely) to your top 3 stressors
  • We identify blockers, hidden dependencies, and blind spots
  • We co-create a priority map (not a backlog)
  • We give you options — real ones — based on your resources
And yes, sometimes the first thing we recommend is “take a beat and fix your internal decision tree.” Other times, it’s “You need an internal audit in 12 days. Here’s the plan.”
Either way, you’ll leave that first engagement knowing exactly where to begin. Not theoretically — tactically.
Progress Doesn’t Start With a Plan. It Starts With Leadership.
At the risk of sounding a little bold: we don’t sell deliverables. We sell movement.
Our job is to take clinical-stage companies and get them unstuck — whether that’s on the road to commercialization or just trying to survive inspection week.
We’re not here to hand you another binder. We’re here to lead from the front.
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The Myth of the Plug-and-Play Consultant